A case report of leucine rich glioma inactivated 1-antibody encephalitis with autonomic dysfunction
10.3760/cma.j.cn113694-20190612-00353
- VernacularTitle:以自主神经功能异常为首发症状的富亮氨酸胶质瘤失活1蛋白抗体相关脑炎一例
- Author:
Jiangman SONG
1
;
Aizhen SHENG
;
Xiangyu ZENG
;
Tao GONG
;
Yuhui CHEN
Author Information
1. 北京医院神经内科，国家老年医学中心 100730 (工作单位为中国航天科工集团七三一医院神经内科，北京 100074)
- From:
Chinese Journal of Neurology
2020;53(5):364-367
- CountryChina
- Language:Chinese
-
Abstract:
Leucine rich glioma inactivated 1 (LGI1) is a protein which is identified as the target involving in autoimmune encephalitis. Seizures and cognitive declines are two main symptoms of LGI1-antibody encephalitis. However, autonomic dysfunction symptoms are not prominent as seizures and cognitive defection and are easily overlooked by physicians. We reported a case with LGI1-antibody encephalitis whose onset symptoms were autonomic dysfunction including sweating, orthostatic hypotension. The features of this case was described in detail and the related literatures were reviewed in order to enhance the knowledge of the disease.
