Calls for the awareness and research on prevention of malignant brain oedema following massive brain infarction
10.3760/cma.j.cn113694-20200114-00040
- VernacularTitle:应当提倡大面积脑梗死后恶性脑水肿的预防理念及其研究
- Author:
Simiao WU
1
;
Ruozhen YUAN
;
Ming LIU
Author Information
1. 四川大学华西医院神经内科，成都 610041
- From:
Chinese Journal of Neurology
2020;53(4):244-249
- CountryChina
- Language:Chinese
-
Abstract:
Massive brain infarction is a major type of severe ischaemic stroke, for which malignant brain oedema is a common cause for poor prognosis. Existing studies and guidelines mostly focused on the intensive care and surgical treatment for malignant brain oedema, whilst there is insufficient evidence to guide the widely applicable interventions specifically targeting malignant brain oedema. We propose that early prediction and prevention may be more feasible and beneficial in practice, than the treatment for malignant brain oedema. Future research is urgently needed to a) dynamically illustrate its natural history and explore the time window for prevention; b) investigate risk factors and early predictors, to guide the selection of high-risk patients for individualised interventions. Clinical doctors should be aware of the importance of early presentation of massive brain infarction, dynamically record changes in symptoms and sign, and provide individualised and comprehensive management, with an aim to reduce the development of malignant brain oedema, and finally reduce stroke burden.
