Autoimmune glial fibrillary acidic protein astrocytopathy
10.3760/cma.j.cn113694-20190603-00329
- VernacularTitle:自身免疫性胶质纤维酸性蛋白星形胶质细胞病
- Author:
Yinxi ZHANG
1
;
Yang ZHENG
;
Chunhong SHEN
;
Meiping DING
Author Information
1. 浙江大学医学院附属第二医院神经内科，杭州 310009
- From:
Chinese Journal of Neurology
2020;53(4):317-320
- CountryChina
- Language:Chinese
-
Abstract:
Autoimmune glial fibrillary acidic protein astrocytopathy is a curable autoimmune inflammatory disease of the central nervous system. Meninges, brain, spinal cord and optic nerve are mainly involved. Radial paraventricular enhancement and/or long segment lesions of spinal cord with central enhancement can be seen on magnetic resonance imaging. Brain biopsy shows perivascular inflammation with microglia activation. The disease is sensitive to steroid therapy. Glial fibrillary acidic protein antibody is considered as a specific biomarker of the disease.
