Research progress on risk factors of tophus formation
10.3760/cma.j.cn114798-20191110-00821
- VernacularTitle:痛风石形成相关危险因素研究进展
- Author:
Lidan MA
1
;
Xinde LI
;
Ying XIN
;
Zhaotong JIA
Author Information
1. 青岛大学附属医院内分泌与代谢性疾病科 266003
- From:
Chinese Journal of General Practitioners
2020;19(6):554-557
- CountryChina
- Language:Chinese
-
Abstract:
Tophus is the sign of chronic gout, which can lead to bone destruction, joint dysfunction, and significantly increase the risk of cardiovascular disease and death. Tophus has a structure of chronic foreign body granuloma,and extracellular reticular trap of neutrophils may be the main mechanism for the formation of tophi. Several factors can lead to the tophus formation. This article reviews the recent advances in the study of biology,risk factors and therapy of tophus.
