Effect of anti-allergic drug combined with deanxit on emotional symptoms and quality of life in elderly patients with allergic rhinitis
10.3760/cma.j.issn.1671-7368.2020.03.011
- VernacularTitle:抗过敏药物联合氟哌噻吨美利曲辛对老年变应性鼻炎患者情绪及生命质量的影响
- Author:
Juebo YU
1
;
Haizhou ZHENG
;
Yuanling ZHUANG
;
Min WANG
;
Junfeng WANG
;
Zexing CHENG
Author Information
1. 扬州大学附属医院耳鼻咽喉-头颈外科 225001
- From:
Chinese Journal of General Practitioners
2020;19(3):242-245
- CountryChina
- Language:Chinese
-
Abstract:
Sixty-three elderly patients with allergic rhinitis and symptoms of anxiety and depression attending in the Affiliated Hospital of Yangzhou University from August 2016 to August 2018 were randomly divided into two groups: 30 patients received deanxit combined with anti-allergic drugs for treatment (study group) and another 30 patients received anti-allergic drugs treatment alone (control group). Subjective nasal obstruction was evaluated by Visual Analogue Scale (VAS), and the quality of life of patients was assessed by Rhinoconjunetivitis Quality of Life Questionnaire (RQLQ).The anxiety and depression mood changes were assessed by Self-rating Anxiety Scale (SAS) sand Self-rating Depression Scale (SDS).The scores of symptoms and mood were compared after 4 weeks and 8 weeks of treatment. The clinical nasal symptoms VAS score, the total RQLQ scores and its 7 domains scores, SDS and SAS scores of patients in two groups were significantly reduced compared to those before treatment ( P<0.05). The VAS score, the total of RQLQ scores and its 7 domains scores, SDS and SAS scores were significantly lower in the study group than those in the control group after 4 weeks and 8 weeks of treatment.The total effective rate of study group was significantly higher than those of the control group (χ 2=6.922, P=0.031; χ 2=11.544, P=0.003). Deanxit combined with anti-allergic drugs shows significant clinical efficacy, it also can improve the symptoms of anxiety and depression, and the quality of life for elderly patients with allergic rhinitis.
