Application of extracorporeal membrane oxygenation for severe acute respiratory distress syndrome after children liver transplantation
10.3760/cma.j.cn421203-20190404-00185
- VernacularTitle:体外膜氧合在肝移植术后儿童重度急性呼吸窘迫综合征中的应用
- Author:
Weili WANG
1
;
Sinan GAO
;
Chao SUN
;
Xingchu MENG
;
Lixin YU
;
Yihe LIU
Author Information
1. 天津市第一中心医院移植外科 300192（现在浙江大学医学院附属第一医院肝胆胰外科，杭州 310003）
- From:
Chinese Journal of Organ Transplantation
2020;41(6):367-371
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the application of extracorporeal membrane oxygenation (ECMO)for severe acute respiratory distress syndrome(ARDS)in children after liver transplantation.Methods:The clinical data were retrospectively analyzed for two ECMO-supported children with severe ARDS after liver transplantation. There were suspected pneumocystis carinii pneumonia(n=1)and identified pneumocystis carinii pneumonia(n=1).Results:Veno-arterial ECMO(VA-ECMO)was performed and oxygen saturation index(OSI)before an initiation of ECMO was 31.8 and 23.9 respectively. Both were successfully separated from ECMO after 219 h and 168 h support respectively, and both were weaned from ventilator after 342 h and 232 h invasive mechanical ventilation respectively. The length of ICU stay was 31 and 18 days and the length of hospital stay 57 and 33 days respectively. During ECMO support, liver function remained stable and there was no new onset of organ dysfunction or life-threatening complications.Conclusions:ECMO is a potential therapy for children with severe ADRS after liver transplantation and the assessment and management of complications with ECMO support should be further studied.
