Application of extracorporeal membrane oxygenation during bilateral lung transplantation
10.3760/cma.j.cn421203-20190916-00353
- VernacularTitle:体外膜氧合在双肺移植术中的应用
- Author:
Jinbo WU
1
;
Minqiang LIU
;
Dongxiao HUANG
;
Huizhi YU
;
Chunxiao HU
;
Yanjuan WANG
;
Jingyu CHEN
Author Information
1. 南京医科大学附属无锡人民医院麻醉科 214023
- From:
Chinese Journal of Organ Transplantation
2020;41(6):337-340
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the effect of extracorporeal membrane oxygenation(ECMO)upon supporting during bilateral lung transplantation(BLTx)for different primary diseases.Methods:The clinical data were retrospectively analyzed for 139 cases of BLTx. They were divided into non-ECMO and ECMO groups. The perieoperative data of two groups were compared.Results:BLTx was successfully performed in all patients. As compared with non-ECMO group, operative duration, mechanical ventilation time and ICU hospitalization time were significantly prolonged in ECMO group ( P<0.05). The proportion of patients with different primary diseases was statistically significant different between two groups( P<0.01). ECMO was employed intraoperatively in all IPAH patients. ECMO proportion was higher in idiopathic pulmonary fibrosis(IPF)patients but lower in chronic obstructive pulmonary disease(COPD)counterparts( P<0.05). In terms of cardiac function indices, patients with a moderate/severe elevation of pulmonary artery pressure had a higher proportion of ECMO application( P<0.001). Moreover, the application of ECMO increased with the severity of tricuspid regurgitation and pulmonary vascular resistance(PVR)( P<0.05). Conclusions:It is both safe and feasible to apply ECMO during BLTx. ECMO support should be given a high priority during BLTx for patients with primary diseases such as IPAH, IPF, severe preoperative PAP, tricuspid regurgitation and PVR. On the other hand, ECMO is sufficient as an alternative choice for COPD patients.
