Evaluation, maintenance and procurement analysis of 128 lung donors from Beijing
10.3760/cma.j.issn.0254-1785.2020.02.010
- VernacularTitle:北京市128例供肺评估、维护及获取情况分析
- Author:
Qianli MA
1
;
Qiduo YU
;
Kunsong SU
;
Li ZHAO
;
Lijuan GUO
;
Lei JING
;
Wenhui CHEN
;
Min LI
;
Zhaoyang LIANG
;
Jingyu CHEN
Author Information
1. 中日友好医院胸外科，北京 100029
- From:
Chinese Journal of Organ Transplantation
2020;41(2):103-106
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To assess the potentials for lung donation among 128 donors (deceased citizens) in 2017 from Beijing.Methods:Gender, age, blood type, duration of ventilation, oxygenation index (PaO 2/FiO 2), chest film and bronchoscopy were analyzed. Results:A total of 5135 deceased Chinese citizens were available for donation in 2017. The rate of donation per million population (PMP) was 3.71. And 463 donors from Beijing were recorded in 2017 and the rate of PMP was 21.05. In 2017, 299 lung transplantations were performed with an average rate of donor lung utility at 5.82%. Among 128 cases assessed for potential lung donors in Beijing, 72 were successfully procured with a percentage of lung utilization of 15.55%. There were 110 males (85.94%) and 18 females (14.06%) with an average age of (39.61±10.67) years. Mechanical ventilation duration was (7.59±2.93) days. The oxygenation rate (PaO 2/FiO 2) was (397.38±105.01) mmHg, (450±67.79) mmHg in procurement group and (338.89±116.15) mmHg in non-procurement group ( P=0.020). The median level of procalcitonin (PCT) was 0.195 ng/ml in procurement group versus 0.349 ng/ml in giving-up group ( P=0.042). Conclusions:Oxygenation rate and PCT level are the independent risk factors for reaching a procurement decision of donor lung. The actual PMP and lung procurement rate in Beijing were both higher than average domestic level (15.55% vs. 5.82%, P=0.000) because of excellent cooperation between Organ Procurement Organization (OPO) and lung transplantation centers. The evaluation of donor lungs and lung maintenance protocols from Beijing should be popularized nationwide.
