Efficacy analysis of pediatric renal transplantations: a report of 202 cases
10.3760/cma.j.issn.0254-1785.2020.01.005
- VernacularTitle:儿童肾移植202例回顾性分析
- Author:
Yonghua FENG
1
;
Zhigang WANG
;
Hongchang XIE
;
Junxiang WANG
;
Jinfeng LI
;
Lei LIU
;
Hua GUO
;
Guiwen FENG
;
Wenjun SHANG
Author Information
1. 郑州大学第一附属医院肾移植科 450052
- From:
Chinese Journal of Organ Transplantation
2020;41(1):20-23
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the efficacies of single-center pediatric transplantations and discuss the current problems.Methods:From July 2007 to September 2019, the clinical data of 202 children (aged ≤17 years) undergoing renal transplantation were reviewed. And their perioperative complications, transplantation outcomes and patient/kidney survival were analyzed.Results:The most common perioperative complication was delayed graft function (DGF)( n=24, 11.9%), recurrence of renopathy ( n=8, 4.0%) and acute rejection ( n=21, 10.4%). The major causes of death and graft failure were lung infection ( n=9, 4.5%) and rejection ( n=11, 5.4%). Perioperative serum creatinine decreased progressively from (816.1±303.1) μmol/L preoperatively to (62.7±20.6) μmol/L at Month 3 post-operation. The value of eGFR were (166.8±37.3), (135.1±29.0) and (109.9±31.1) ml/(min·1.73 m 2) at Year 1/3/5 post-operation respectively. The survival rates were 96.7%, 96.3%, 94.1%, 93.5%, 94.1% and 90.7% at Year 1/3/5 post-operation respectively. No difference existed in human/kidney survival rate between LD and DD groups at Year 1/3/5 post-operation ( P>0.05) and transplantation outcomes were excellent. Conclusions:Effective and successful outcomes have been achieved at our center. And further optimizations are required for resolving various problems.
