Primary hepatic adenosquamous carcinoma: report of 5 cases
10.3760/cma.j.cn113855-20200506-00355
- VernacularTitle:原发性肝脏腺鳞癌五例临床诊治体会
- Author:
Zixiang CHEN
1
;
Jiangming CHEN
;
Qi GUO
;
Qingsong XIE
;
Qiang FANG
;
Tian PU
;
Ming CAI
;
Kun XIE
;
Yijun ZHAO
;
Xiaoping GENG
;
Fubao LIU
Author Information
1. 安徽医科大学第一附属医院肝胆胰外科，合肥 230001
- From:
Chinese Journal of General Surgery
2020;35(11):874-878
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the clinicopathological characteristics of the primary hepatic adenosquamous carcinoma(ASC).Methods:A retrospective analysis was performed on the clinical data of 5 ASC patients admitted to the First Affiliated Hospital of Anhui Medical University from 2006 to 2019 who underwent surgical resection and were pathologically confirmed.Results:Among the 5 ASC cases, there were 4 males and 1 female. The age ranged from 48 to 73 years. As for the initial symptoms, there were 5 cases complaining upper abdominal pain, 2 cases presenting fever, 1 case presenting weight loss and 1 case presenting jaundice. CA19-9 was significantly higher than normal in 4 cases, while AFP was normal in all. None had definite preoperative diagnosis.All the 5 patients underwent surgical resection with pathology proved primary hepatic ASC. Lymph node metastasis was found in 4 cases and nerve invasion in 2 cases. There were 4 cases at TNM stage ⅣA, one at stage ⅠB. The median disease-free survival (DFS) was 5 months and the overall survival (OS) was 9 months.Conclusions:Primary hepatic adenosquamous carcinoma is a rare type of liver malignant tumor with an extremely poor prognosis. Surgical resection helps little in improving the prognosis.
