A new nano carbon lymph tracing method for gastric cancer patients after neoadjuvant chemotherapy
10.3760/cma.j.cn113855-20200323-00234
- VernacularTitle:一种对新辅助化疗后胃癌患者纳米碳淋巴示踪方法的应用
- Author:
Junli ZHANG
1
;
Yiping JIN
;
Sen LI
;
Pengfei MA
;
Yanghui CAO
;
Chenyu LIU
;
Xijie ZHANG
;
Guangsen HAN
;
Yuzhou ZHAO
Author Information
1. 郑州大学附属肿瘤医院普外科 450000
- From:
Chinese Journal of General Surgery
2020;35(10):788-791
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate a new nano-carbon lymphatic tracing method to increase the number of lymph nodes acquired in patients with neoadjuvant chemotherapy for gastric cancer.Method:From Jan 2015 to Mar 2016, 159 patients with gastric cancer were recruited including 66 cases in study group receiving nano carbon injection under the mucosa layer one day before the operation, and 93 cases with intraoperative subserosal layer injection as control.Results:The average number of lymph nodes obtained in the study group was 47.0±14.7, while that in control was 38.0±14.5, P<0.05. The number of fibrotic lymph nodes obtained in the study group was 3.1 ± 1.9, compared with 3.0±1.8 in control, P>0.05. The number of black-stained lymph nodes in the former was 22.3±4.4, and the later was 14.7±4.8, P<0.05. The lymph nodes harvested in the first station in study group was 26.6±8.5, while that in the control group was 24.1±9.9, P>0.05. The lymph nodes obtained in the second station was 20.4±6.9 in study group, while in control was 13.8±5.7, P<0.05. Conclusions:The submucosal injection of nanocarbon one day before surgery increase the number of lymph nodes obtained in gastric cancer patients with neoadjuvant chemotherapy.