Primary retroperitoneal liposarcoma surgery in combination of bowel resection, a report of 24 cases
10.3760/cma.j.cn113855-20200429-00332
- VernacularTitle:原发性腹膜后脂肪肉瘤切除术中联合肠切除的临床疗效分析
- Author:
Jun CHEN
1
;
Nannan YAN
;
Lili FENG
;
Mengmeng XIAO
;
Mei HUANG
;
Xiaobing CHEN
;
Chenghua LUO
Author Information
1. 北京大学国际医院腹膜后肿瘤外科 102206
- From:
Chinese Journal of General Surgery
2020;35(10):778-781
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate primary retroperitoneal liposarcoma surgeries in combination with involved bowel resection .Methods:Clinical data of primary retroperitoneal liposarcoma patients admitted for surgery at Peking University International Hospital from Jan 2015 to July 2019 were retrospectively reviewed.Results:Twenty-four patients undergoing resectional surgeries combining with bowel resection were included for the study, of which 6 cases underwent right hemicolectomy, 8 did left hemicolectomy, 6 did sigmoidectomy, 2 did proctectomy and 8 did small bowel resection. The post operative morbidity was 38%. 2 of 24 had anastomotic fistula. There was no mortality. Final pathology disclosed well differentiated liposarcoma in 13 and dedifferentiated liposarcoma in 11 cases. 18 cases were confirmed with bowel infiltration pathologically. All patients were followed up after the surgery. After a median of 25 months following up, 8 cases developed recurrences and 3 deceased. Two-year overall survival and progression free survival probability were 91% and 71% respectively. Dedifferentiated liposarcoma as a pathological type was found as the only risk factor associated to poor progression free survival ( Z=2.02, P=0.042). Conclusion:Combining resection of primary retroperitoneal liposarcoma with involved bowel was relatively safe, with low morbidity, increasing tumor clearance. Dedifferentiated liposarcoma is associated wth poor prognosis.
