Effect of expanded lymphadenectomy on the survival rate of patients with resectable hilar cholangiocarcinoma
10.3760/cma.j.cn113855-20200104-00011
- VernacularTitle:扩大淋巴结清扫对肝门胆管癌根治术患者生存率的影响
- Author:
Yilei DENG
1
;
Jian LI
;
Wenjie MA
;
Fuyu LI
;
Longshuan ZHAO
Author Information
1. 郑州大学第一附属医院肝胆胰外科 450000
- From:
Chinese Journal of General Surgery
2020;35(9):677-680
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effect of expanded lymphadenectomy on the survival rate of the patients with hilar cholangiocarcinoma(HC).Methods:The clinical data of 129 patients undergoing radical resection of HC were retrospectively analyzed. According to the range of lymphadenectomy, they were divided into regional group(91 cases) and expanded group(38 cases). The clinical data, survival rate and postoperative complications in two groups were compared and analyzed.Results:The 3-year and 5-year survival rates of metastasis free(M0) patients in the regional group and expanded group were 44.1%, 24.8% and 47.0%, 33.6%, respectively; there were no statistically significant difference in survival rates between the two groups(χ 2=0.662, P=0.416). Compared with patients in the regional group, the average number of harvested lymph nodes in the expanded group was significantly increased and the difference was statistically significant( t=14.678, P=0.000), while the incidence of severe complications and mortality does not increase significantly. Conclusion:Expanded lymphadenectomy did not improve the survival rate of M0 HC patients, which while yielding more lymph nodes does not increase the incidence of postoperative complications and mortality in resectable HC patients.
