Laparoscopic side-to-side jejunoileal anastomosis for the treatment of non-obese type 2 diabetes mellitus
10.3760/cma.j.cn113855-20191207-00720
- VernacularTitle:非肥胖性2型糖尿病患者腹腔镜下空回肠侧侧吻合术的疗效分析
- Author:
Jupeng YANG
1
;
Hu JIN
;
Hongyi ZHANG
;
Chunlei DAI
;
Yang GU
;
Ming LIU
;
Tieliang SUN
;
Zhonghui WANG
;
Hongliang LYU
Author Information
1. 吉林省一汽总医院普外二科，长春 130011
- From:
Chinese Journal of General Surgery
2020;35(7):550-553
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the feasibility, safety and clinical efficacy of laparoscopic side-to-side jejunoileal anastomosis in the treatment of non-obese type 2 diabetes patients (BMI≤32.5 kg/m 2). Methods:The clinical data of 135 patients who underwent laparoscopic side-to-side jejunoileal anastomosis at our hospital from Jan 2018 to Oct 2018 were retrospectively analyzed. They were followed up for 12 months until the end of Oct 2019. SPSS software was used to compare patients′ fasting blood glucose, glycosylated hemoglobin, c-peptide, insulin, body weight, BMI with the values after 12 months of the surgery, and then evaluate factors affecting the prognosis.Results:135 patients successfully completed laparoscopic side-to-side jejunoileal anastomosis without conversion to open surgery. After 12 months of the operation, the patients′ fasting blood glucose was (5.80±0.18)mmol/L, glycosylated hemoglobin was 5.9%±0.4%, fasting c-peptide was(1.32±0.21) nmol/L, and fasting insulin was (42±54) mU/L ( t=10.654, 12.657, 11.214, 10.698, all P<0.05). The body weight was (72.4±9.9)kg, BMI was( 25.6±2.8)kg/m 2, and the difference was not statistically significant ( t=7.658, 6.958, P>0.05). In patients with preoperative glycosylated hemoglobin controlled below 8% and the duration of T2DM less than 10 years, the chances being cured was better than that of those with glycosylated hemoglobin>8% and the medical history >10 years. Conclusion:Laparoscopic side-to-side jejunoileal anastomosis in the treatment of non-obese type 2 diabetes is effective, safe and reliable.
