Effect of splenic artery ligation on liver function recovery and hypersplenism during liver transplantation
10.3760/cma.j.cn113855-20190808-00457
- VernacularTitle:肝移植术中脾动脉结扎对肝功能恢复及脾功能亢进的影响
- Author:
Chaojie XIONG
1
;
Zhewei YU
;
Yangke HU
;
Caidei LU
;
Jing HUANG
Author Information
1. 宁波大学医学院，浙江省 315211
- From:
Chinese Journal of General Surgery
2020;35(7):516-520
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the efficacy of splenic artery ligation on liver function recovery and hypersplenism in liver transplant patients with end-stage liver disease complicating portal hypertension and hypersplenism.Methods:From Jan 2016 to Jan 2019, the clinical data of patients undergoing liver transplantation at our hospital were analyzed retrospectively, among which 53 patients were enrolled in the study with end-stage liver disease complicated with portal hypertension and hypersplenism. Patients were divided into ligation group( n=23) and no ligation group( n=30). The serum liver function and white blood cells, platelets and postoperative complications were compared. Results:20 pairs of patients were successfully matched by PSM method. All patients were followed up for over 6 months.There was no statistically significant difference between the two groups in all the observation points within 2 weeks after operation; Within 6 months, there was no statistically significant difference in WBC, platelet and Hgb.Statistically significant differences in postoperative complications such as infection, gastrointestinal bleeding, and splenic artery stealing syndrome were also not found between these two groups.Conclusions:Splenic artery ligation during liver transplantation does not accelerate liver function recovery nor ameliorate hypersplenism.
