Thrombo-pretreatment in AngioJet mechanical thrombectomy

VernacularTitle:术前血栓预处理在AngioJet治疗下肢深静脉血栓形成中的作用
Author: Zhang ZHANG ¹ ; Songlin GUO ; Jikai YIN ; Dong WANG ; Lei WANG
Author Information

1. 空军军医大学唐都医院普通外科，西安　710038
From: Chinese Journal of General Surgery 2020;35(5):384-388
CountryChina
Language:Chinese
Abstract: Objective:To evaluate thrombo-pretreatment in AngioJet mechanical thrombectomy.Methods:68 acute DVT patients were randomized into two groups: thrombo-pretreatment with low-dose urokinase via popliteal vein before operation (experimental group)comparing with those undergoing upfront surgery.Results:After pretreatment, the immediate thrombus clearance grade in the experimental group was higher than that in the control group( Z=2.446, P=0.014), the procedure time was shorter [(289.1±57.9) s vs. (342.3±75.2) s] and less hemoglobin decreased after operation [(7.2±2.4) g/L vs. (11.4±2.1) g/L]. There was no difference in the deep vein patency and the incidence of PTS between the two groups at 3 , 12 and 24 months after operation. Conclusion:Pre-treatment with low dose urokinase before operation can improve the efficiency of PMT, effectively reduce the time of AngioJet activation and the destruction of red blood cells.