Prognostic influencing factors in patients of Barcelona stage B hepatocellular carcinoma undergoing hepatectomy
10.3760/cma.j.cn113855-20191015-00599
- VernacularTitle:巴塞罗那B期肝细胞癌手术治疗预后影响因素分析
- Author:
Yonghan ZHANG
1
;
Chixian ZHANG
;
Dexu LI
Author Information
1. 郑州大学第一附属医院肝胆外科 450000
- From:
Chinese Journal of General Surgery
2020;35(3):215-218
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the prognostic factors that influence Barcelona (Barcelona clinical liver cancer staging system, BCLC)stage B hepatocellular carcinoma patients after hepatectomy.Methods:Retrospective analysis was made on clinical and pathological data of 50 standardized hemihepatectomy in Barcelona stage B hepatocellular carcinoma from 2013 to 2017.Results:Single-factor results showed that high expression of tumor microvascular invasion (MVI) and proliferation of nuclear antigen (Ki-67) were the prognostic factors ( respectively χ 2 =8.411, 10.939, all P<0.05). Multivariate analysis showed that the difference of high expression of Ki-67 and survival rate was statistically significant (respectively F=5.710, 8.254, all P<0.05). Ki-67 expression level and tumor differentiation were statistically significant (χ 2=0.497, P<0.05). There was a statistically significant difference in survival between the high-risk group and the low-risk group according to the risk factors (χ 2=12.152, P<0.05). Conclusions:MVI and high expression of Ki-67 were high risk factors affecting the overall survival rate of liver cancer after hemihepatectomy.
