Clinical significance of large spontaneous portosystemic shunts in Budd-Chiari syndrome
10.3760.cma.j.issn.1007-631X.2020.02.010
- VernacularTitle:布-加综合征合并大口径自发性门-体分流患者的临床特征分析
- Author:
Xiaowei DANG
1
;
Qingbo MENG
;
Luhao LI
Author Information
1. 郑州大学第一附属医院肝胆胰外科河南省布-加综合征诊疗中心
- Keywords:
Budd-Chiari syndrome;
Hypertension,portal;
Collateral circulation
- From:
Chinese Journal of General Surgery
2020;35(2):124-127
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical significance of large spontaneous portosystemic shunts (L-SPSS) in Budd-Chiari syndrome (B-CS).Methods Clinical data of 382 B-CS patients treated at the First Affiliated Hospital of Zhengzhou University from Apr 2012 to Dec 2018 were analyzed retrospectively and we included 32 patients with B-CS complicated L-SPSS (diameter ＞ 8 mm).65 patients without L-SPSS were selected randomly to form the control group.The correlation between L-SPSS and liver function,upper gastrointestinal bleeding,ascites,hepatic encephalopathy,inferior vena cava thrombosis,portal vein diameter and splenic vein diameter were analyzed.Results TBil,Child-Pugh scores,incidence of hepatic encephalopathy,ascites and inferior vena cava thrombosis in the B-CS complicated L-SPSS group were higher than that in the B-CS without L-SPSS group.The percentage of Child-Pugh grade B and C patients in the B-CS complicated L-SPSS group were also higher than that in the B-CS without L-SPSS group.The level of ALB and hepatic volume per unit surface area were both significantly less in the experimental group.(P ＜0.05).There were no statistics differences in incidence of upper gastrointestinal bleeding and MELD scores between the two groups (P ＞ 0.05).Conclusions For those B-CS patients complicated L-SPSS,hepatic encephalopathy and ascites are more frequent,and they usually have poorer liver function.
