The role and significance of surgical intervention in the diagnosis and treatment of autoimmune pancreatitis
10.3760/cma.j.issn.1007-631X.2020.02.007
- VernacularTitle:外科干预在自身免疫性胰腺炎诊断及治疗中的意义
- Author:
Shifeng YANG
1
;
Guangming SUN
;
Fengyu TIAN
;
Jisheng HU
;
Hua CHEN
;
Xinjian LYU
;
Bei SUN
;
Rui KONG
Author Information
1. 哈尔滨医科大学附属第一医院胰胆外科 150000
- Keywords:
Pancreatitis;
Pathology,clinical;
Surgical intervention
- From:
Chinese Journal of General Surgery
2020;35(2):112-115
- CountryChina
- Language:Chinese
-
Abstract:
Objective To summarize the clinical characteristics of autoimmune pancreatitis (AIP) and discuss the role and significance of surgical intervention in the treatment of AIP.Methods The clinical data of 11 patients with preoperative confirmed AIP and 8 patients with preoperative suspected AIP receiving surgical intervention at the First Affiliated Hospital of Harbin Medical University from 2011 to 2017 were retrospectively analyzed.Results Among 11 preoperatively confirmed AIP patients,9 (47.4％) underwent endoscopic retrograde cholangiopancreatography (ERCP) with nasal bile duct implantation or biliary stent drainage,and 2 (10.5％)underwent choledochojejunostomy.Among 8 putative AIP patients in which a cancer was suspected 4 (21.1％) underwent choledochojejunostomy,3 (15.8％) did pancreaticoduodenectomy,and 1 (5.3％) had distal pancreatectomy plus splenectomy.Postoperative pathology confirmed pancreatic cancer in 3 cases,IPMN in 1 case.Conclusions While autoimmune pancreatitis is IgG4 related disease,surgical intervention is indicated when there is poor response to drug treatment or when a cancer is to be ruled out.
