Role of melanocytes and relevant cell populations in the occurrence of vitiligo
10.35541/cjd.20190353
- VernacularTitle:黑素细胞及相关细胞群参与白癜风发病的研究进展
- Author:
Ai′e XU
1
;
Miaoni ZHOU
;
Fuquan LIN
Author Information
1. 杭州市第三人民医院皮肤科 310009
- From:
Chinese Journal of Dermatology
2020;53(9):751-754
- CountryChina
- Language:Chinese
-
Abstract:
The pathogenesis of vitiligo is complicated, and the loss of melanocytes plays a central role. Besides deficiency in melanocytes, it is considered that dysfunction of epidermal and dermal cell populations as well as their interaction with melanocytes also play important roles in the occurrence of vitiligo, Thus, it is necessary for understanding and treatment of vitiligo to fully and accurately understand pathophysiological states of full-thickness vitiliginous skin cells and tissues at different stages. This review aims to summarize research progress in the role of melanocytes and related cell populations in the occurrence of vitiligo.