Application of phototherapy in cutaneous T-cell lymphomas
- VernacularTitle:光疗在皮肤T细胞淋巴瘤中的应用进展
- Author:
Xuyue ZHOU
1
;
Chao LUAN
;
Kun CHEN
Author Information
- From: Chinese Journal of Dermatology 2020;53(9):764-767
- CountryChina
- Language:Chinese
- Abstract: Cutaneous T-cell lymphomas (CTCL) are malignancies derived from T cells. The aim of its treatment is to control symptoms and achieve long-term remission, and phototherapy alone or in combination is one of important treatment methods. Phototherapy of CTCL includes psoralens and ultraviolet A radiation, narrowband and broadband ultraviolet B radiation, extracorporeal photochemotherapy, photodynamic therapy, ultraviolet A1 radiation, 308-nm excimer laser, and so on. Efficacy of phototherapy is associated with various factors, such as stage of disease, sites of lesions, types of skin photoreaction, etc. In clinical practice, phototherapy involves clearance, consolidation and maintenance phases, but it is still disputed whether maintenance treatment can control the recurrence of CTCL. Understanding action mechanisms, indications, therapeutic effects and adverse effects of phototherapy is helpful in selecting the best treatment protocol.
