Successful treatment of three cases of livedoid vasculopathy with rivaroxaban alone or in combination
10.35541/cjd.20190100
- VernacularTitle:联合或者单独使用利伐沙班治疗青斑样血管病三例
- Author:
Shijia RAO
1
;
Ji LI
;
Hongfu XIE
;
Wei SHI
;
Qianjin LU
Author Information
1. 中南大学湘雅二医院皮肤科
- Keywords:
Skin diseases,vascular;
,Anticoagulants;
Treatment outcome;
Livedoid vasculopathy;
Rivaroxaban
- From:
Chinese Journal of Dermatology
2020;53(3):226-228
- CountryChina
- Language:Chinese
-
Abstract:
Livedoid vasculopathy is a rare chronic ischemic necrotic skin disease caused by microvascular thrombosis in superficial vascular plexuses.Effective treatments are lacking.Efficacy of anticoagulants has been clinically proven in the treatment of this disease,but the administration route and adverse reactions limit their extensive application.The new oral factor Xa inhibitor rivaroxaban,which has many advantages,such as no need for coagulation monitoring,few adverse reactions and convenient oral administration,can be used in the prevention and treatment of thrombosis and post-thrombotic ulcers.In this article,3 patients with livedoid vasculopathy were treated with rivaroxaban alone or in combination,and satisfactory efficacy was obtained.