The predictive value of serum alkaline phosphatase combined with parathyroid hormone in all-cause and cardiovascular mortality in maintenance hemodialysis patients

VernacularTitle:联合检测血清碱性磷酸酶和甲状旁腺激素对维持性血液透析患者全因及心血管事件死亡风险的预测价值
Author: Xiaohan LU ¹ ; Haixia LIN ; Minghui GENG ; Xiaoyan WU ; Ping GAO
Author Information

1. 武汉大学中南医院肾内科　430071
From: Chinese Journal of Internal Medicine 2020;59(8):634-637
CountryChina
Language:Chinese
Abstract: To analyze the predictive value of serum intact parathyroid hormone (iPTH) and alkaline phosphatase (ALP) on all-cause and cardiovascular mortality in maintaining hemodialysis (MHD) patients. A total of 224 MHD patients were prospectively investigated and followed up for 2 years. Serum iPTH levels were not associated with all-cause death and cardiovascular death ( HR=1.001, 95% CI 1.000-1.004, P=0.048) . The level of serum ALP was associated with cardiovascular death ( HR=1.002, 95% CI 1.000-1.004, P=0.033) . ALP≥106 IU/L was an independent risk factor for cardiovascular death in MHD patients ( P<0.05) . The joint variable was correlated with mortality in MHD patients ( HR=1.002, 95% CI 1.000~1.004, P=0.033) , that equal or over 37.28 was an independent risk factor for mortality ( P<0.05).