Transient Pseudohypoaldosteronism in an Infant with Vesicoureteral Reflux.
- Author:
Moon Kyu KIM
1
;
Sung Eun PARK
;
Jun Ho LEE
Author Information
1. Department of Pediatrics, CHA Bundang Medical Center, CHA University, Seongnam, Korea. naesusana@yahoo.co.kr
- Publication Type:Case Report
- Keywords:
Failure to thrive;
Infant;
Pseudohypoaldosteronism;
Vesicoureteral reflux
- MeSH:
Acidosis;
Aldosterone;
Dehydration;
Failure to Thrive;
Humans;
Hyperkalemia;
Hyponatremia;
Infant;
Plasma;
Potassium;
Pseudohypoaldosteronism;
Sodium;
Urinary Tract Infections;
Vesico-Ureteral Reflux
- From:Journal of the Korean Society of Pediatric Nephrology
2012;16(1):54-57
- CountryRepublic of Korea
- Language:English
-
Abstract:
A 6-month-old boy with vesicoureteral reflux exhibited features of transient type 1 pseudohypoaldosteronism (PHA) in the course of urinary tract infection. PHA presents hyponatremia, hyperkalemia, and metabolic acidosis, accompanying with high urinary sodium, low potassium excretion, and high plasma aldosterone concentration. Severe electrolyte disturbance can occur in an infant with vesicoureteral reflux because of secondary PHA. Appropriate treatment of dehydration and sodium supplementation induces rapid improvement of electrolyte imbalance and metabolic acidosis resulting from secondary PHA associated with vesicoureteral reflux.