Association between carcinoembryonic antigen and metabolic syndrome in females
10.3760/cma.j.cn311282-20200227-00109
- VernacularTitle:女性健康体检人群的癌胚抗原与代谢综合征关系研究
- Author:
Jingru LI
1
;
Yafei LIU
;
Xiangyun LI
;
Fang TANG
Author Information
1. 潍坊医学院公共卫生学院 261053
- From:
Chinese Journal of Endocrinology and Metabolism
2020;36(11):926-931
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the relationship between carcinoembryonic antigen (CEA) and metabolic syndrome (MetS) in females.Methods:The study involved 11337 women who visited the health check-up system in Health Management Center of a general hospital in Shandong province between January 2014 and December 2015. By grouping CEA by quartiles, logistic regression models were used to analyze the relationship between CEA and MetS and its components.Results:The prevalence of MetS was 16.4 %, and abnormal levels of CEA accounted for 7.1% of patients with MetS which exceeded the general physical examination population (3.2%). The level of CEA increased with the increase of the number of metabolic components. The multivariate logistic regression analysis showed that people with high levels of carcinoembryonic antigen were at higher risk for metabolic syndrome( χ2=18.374, P<0.01). Compared with the level of CEA in Q1, CEA levels in Q2, Q3, and Q4 were statistically related to MetS. The OR values were 1.25(95% CI 1.03-1.52), 1.25(95% CI 1.03-1.51) and 1.42(95% CI 1.17-1.72), respectively. Conclusion:For females, the study suggests that there is a relationship between CEA and MetS. The increased CEA level in patients with MetS should be carefully explained in clinical practice.
