Prolonged duration of positive virus-PCR results in patients with COVID-19 may be associated with diabetes mellitus
10.3760/cma.j.cn311282-20200309-00147
- VernacularTitle:新型冠状病毒肺炎患者核酸阳性持续时间延长可能与合并糖尿病相关
- Author:
Xin GUAN
1
;
Haixia GUAN
;
Ye GU
;
Luping LI
;
Leishi WANG
;
Yan WANG
;
Haoge QIN
;
Yunfei GAO
;
Xiaomei WANG
Author Information
1. 沈阳市第六人民医院内分泌科 110006
- From:
Chinese Journal of Endocrinology and Metabolism
2020;36(8):661-666
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the correlation between concomitant diabetes mellitus and clinical features in patients with COVID-19.Methods:Fifty patients with COVID-19 admitted to the Sixth People′s Hospital of Shenyang were divided into 2 groups with and without diabetes mellitus. Indexes such as hospitalization days, duration of positive virus-PCR result, secondary infection, duration of fever, rate of liver dysfunction, and rate of cardiac injury were compared between 2 groups.Results:The average hospitalization durations of diabetes group and control group were(24.0±6.8) and(18.4±5.9) days, respectively, and the duration of positive virus-PCR testing results were(16.0±4.5) and(12.3±4.4) days respectively, suggesting longer hospital stay and longer time for virus clearance in the diabetes group than those in the control group(both P<0.05). The rates of secondary infection, severe subtype, liver dysfunction and cardiac injury in the diabetes group increased, though without significant difference( P>0.05). Conclusion:Prolonged duration of positive virus-PCR result and average days of hospitalization in patients with COVID-19 may be associated with diabetes mellitus.
