Relationship between preoperative hypoalbuminemia and pulmonary complications after pneumonectomy
10.3760/cma.j.cn131073.20200322.00707
- VernacularTitle:术前低白蛋白血症与肺切除术后肺部并发症的关系
- Author:
Menghan SUN
1
;
Meng MAO
;
Jie SUN
Author Information
1. 南京医科大学第一附属医院麻醉科 210029
- From:
Chinese Journal of Anesthesiology
2020;40(7):795-799
- CountryChina
- Language:Chinese
-
Abstract:
A retrospective analysis was performed on the clinical data of patients with normal lung function who underwent elective thoracoscopic lung resection for the first time in our hospital from January 2018 to December 2018.According to the minimum serum albumin level obtained within 48 h before operation, the patients were divided into hypoalbuminemia group (<35 g/L) and normal albumin level group (≥35 g/L). The perioperative baseline data and intraoperative and postoperative conditions were compared between the two groups after propensity score matching.The risk factors for postoperative pulmonary complications (PPCs) in the perioperative period were analyzed by logistic regression analysis, and the patients were divided into complication group and non-complication group according to whether PPCs occurred.Among the 1 127 patients enrolled in the study, there were 306 cases in complication group, and 821 cases in non-complication group.Logistic regression analysis showed that hypoalbuminemia was an independent risk factor for PPCs in the patients undergoing thoracoscopic lung resection ( OR=1.643, 95% confidence interval 1.201-2.249, P<0.05). After matching the propensity score, there were 498 cases in normal albumin group and 178 cases in hypoalbuminemia group.The total incidence of PPCs and incidence of pneumonia were significantly higher in hypoalbuminemia group than in normal albumin level group ( P<0.05). In summary, preoperative hypoalbuminemia is a risk factor for pulmonary complications after pneumonectomy.
