Relationship between preoperative long-term sleep disorder and postoperative hyperalgesia in patients undergoing cardiac surgery
10.3760/cma.j.cn131073.20190829.00605
- VernacularTitle:心脏手术患者术前长期睡眠障碍与术后痛觉过敏的关系
- Author:
Hongbai WANG
1
;
Liang ZHANG
;
Fuxia YAN
;
Su YUAN
;
Zhe ZHANG
;
Yu ZHANG
Author Information
1. 北京协和医学院 中国医学科学院 阜外医院麻醉中心 100037
- From:
Chinese Journal of Anesthesiology
2020;40(6):660-663
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the relationship between preoperative long-term sleep disorder and postoperative hyperalgesia in the patients undergoing cardiac surgery.Methods:One hundred and eighty-one adult patients of both sexes, aged 18 yr, undergoing elective cardiac valve surgery under cardiopulmonary bypass with general anesthesia, were enrolled in this study.On 1st day before surgery, the Pittsburgh Sleep Quality Index questionnaire was used to assess the patient′s sleep quality in the last month.When Pittsburgh Sleep Quality Index score was more than 5, the patient was considered to have long-term sleep disorder.Postoperative analgesia was performed with sufentanil.Patients were divided into 2 groups according to the numeric rating scale (NRS) score: non-hyperalgesia group (NHA group, NRS score <4) and hyperalgesia group (HA group, NRS score ≥4). A multivariate logistic regression was used to identify the risk factors associated with postoperative hyperalgesia.Results:The results of logistic regression analysis found that smoking and preoperative long-term sleep disorder were independent risk factors for postoperative hyperalgesia.Conclusion:Preoperative long-term sleep disorder may induce hyperalgesia after cardiac surgery in patients.
