Risk factors for weaning failure after mandibular distraction osteogenesis in infants with Pierre Robin sequence
10.3760/cma.j.cn131073.20190723.00321
- VernacularTitle:Pierre Robin序列征婴儿下颌骨牵引术后撤机失败的危险因素
- Author:
Na ZHANG
1
;
Zhe MAO
;
Yonghong TAN
;
Yingqiu CUI
;
Yingyi XU
;
Xingrong SONG
Author Information
1. 广州医科大学附属广州市妇女儿童医疗中心麻醉科 510623
- From:
Chinese Journal of Anesthesiology
2020;40(3):338-341
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To identify the risk factors for weaning failure after mandibular distraction osteogenesis in the infants with Pierre Robin sequence.Methods:A retrospective cohort study was conducted to collect clinical records of infants with Pierre Robin sequence underwent mandibular distraction osteogenesis at Guangzhou Women and Children′s Medical Center from November 2016 to May 2019.The inclusion criteria consisted of the following: age <1 yr and no serious cardiopulmonary disease or serious airway malformation.The medical charts were reviewed for sex, age, weight, premature delivery, low birth weight, preoperative intubation, preoperative pulmonary infection, ventilator-associated pneumonia, as well as mechanical ventilation time and distraction length at first weaning.The infants were divided into 2 groups according to the outcome of ventilator weaning at first attempt: successful group and failure group.The risk factors of which P values were less than 0.05 would enter the logistic regression analysis to stratify weaning failure-related risk factors. Results:A total of 140 infants were included in this study, of which 9 cases developed failure of weaning at first attempt after operation, with the incidence of 6.4%.The results of logistic regression analysis showed that the distraction length and incidence of ventilator-associated pneumonia were independent risk factors for weaning failure after operation ( P<0.05). Conclusion:The length of distraction and ventilator-associated pneumonia are independent risk factors for weaning failure after mandibular distraction osteogenesis in the infants with Pierre Robin sequence.
