Application and research progress of liquid biopsy in renal cell carcinoma
10.3760/cma.j.cn112330-20200723-00557
- VernacularTitle:液体活检技术在肾细胞癌中的应用及研究进展
- Author:
Ruotao XIAO
1
;
Cheng LIU
;
Lulin MA
Author Information
1. 北京大学第三医院泌尿外科 100191
- From:
Chinese Journal of Urology
2020;41(11):873-876
- CountryChina
- Language:Chinese
-
Abstract:
Liquid biopsy is a noninvasive analysis of tumor related substances in fluid samples, which overcomes the limitations of traditional histological biopsy, and beneficial for early diagnosis and differentiation, prediction of response to treatment, longitudinal monitoring of disease progression and prediction of prognosis. Renal cell carcinoma is lack of mature serum tumor markers, and the diagnosis and monitoring of the disease still rely on imaging. In recent years, liquid biopsy has become a hotspot in renal cell carcinoma. In this paper, we will review the application and research progress of circulating tumor cells (CTCs), circulating tumor DNA (ctDNA), circulating tumor RNA (ctRNA), exosomes, tumor "education" platelets (TEPs) in renal cell carcinoma.
