Progress in detection and clinical application of circulating tumor cells in renal cell carcinoma
10.3760/cma.j.issn.1000-6702.2020.02.016
- VernacularTitle:肾癌循环肿瘤细胞检测及临床应用的研究进展
- Author:
Xin DU
1
;
Baoan HONG
;
Qiang ZHAO
;
Yongpeng JI
;
Yong YANG
;
Ning ZHANG
Author Information
1. 北京大学肿瘤医院暨北京市肿瘤防治研究所泌尿外科恶性肿瘤发病机制及转化研究教育部重点实验室 100142
- Keywords:
Carcinoma,renal cell;
Circulating tumor cells (CTCs);
Biomarker
- From:
Chinese Journal of Urology
2020;41(2):153-156
- CountryChina
- Language:Chinese
-
Abstract:
Renal cell carcinoma is one of the common malignant tumors in genitourinary cancer.20％-30％ of patients have distant metastases.However,current biomarkers used for diagnosis,recurrence monitoring,and prognosis assessment are still uncertain.Circulating tumor cells (CTCs) are tumor cells that are detached from the primary tumor or metastases,and invade and presenting in peripheral blood vessels.Therefore,CTCs is regarded as a key step in the process of tumor metastasis.However,current studies on CTCs of renal cell carcinoma are facing with problems such as inconsistent detection methods and limited clinical applications.This article reviews the progress in the detection and clinical application of CTCs of renal cell carcinoma.
