Characteristics and diagnosis of concurrent infections in patients with acute-on-chronic liver failure
10.3760/cma.j.issn.1674-2397.2020.02.012
- VernacularTitle:慢加急性肝衰竭患者并发感染的特点及对诊断的影响
- Author:
Gaoxiang YING
1
;
Ying YANG
;
Fengtian WU
;
Zhi CHEN
Author Information
1. 浙江大学医学院附属第一医院 传染病诊治国家重点实验室，感染性疾病诊治协同创新中心，国家感染性疾病临床医学研究中心，杭州 310003
- From:
Chinese Journal of Clinical Infectious Diseases
2020;13(2):140-148
- CountryChina
- Language:Chinese
-
Abstract:
Acute-on-chronic liver failure (ACLF) is a clinical syndrome characterized by chronic liver disease, multiple organ failure and high mortality. ACLF patients have a high incidence of concurrent infection due to immune dysfunction. Early diagnosis of concurrent infection can initiate early anti-infection treatment and improve patient prognosis. However, ACLF complicated with infection is easy to be misdiagnosed, so searching for new diagnostic methods and biomarkers of infection can improve the reliability and accuracy of diagnosis. This article reviews the progress on epidemiology and immune-related characteristics, and their effect on diagnosis of concurrent infection in patients with ACLF.
