Application of α-emitters in precision medicine of malignant cancers
10.3760/cma.j.cn321828-20191008-00217
- VernacularTitle:α核素在恶性肿瘤精准医疗中的应用
- Author:
Mengdie YANG
1
;
Xin FAN
;
Shanshan QIN
;
Fei YU
Author Information
1. 同济大学附属第十人民医院核医学科，上海 200072
- From:
Chinese Journal of Nuclear Medicine and Molecular Imaging
2020;40(11):693-697
- CountryChina
- Language:Chinese
-
Abstract:
With high linear energy transfer (LET) and short transmission distance, targeted α-therapy (TAT), as a specific targeted tumor treatment, can improve the killing effect on microscopic lesions or diffuse micrometastases. It can reduce bone marrow toxicity and overcome the problem of radiotherapy tolerance in hypoxic tumors. α-emitters and their labeled drugs are constantly being studied, and further research is needed to promote the development of clinical applications.
