Diagnostic value of 99Tc m-HSA SPECT/CT imaging for protein-losing enteropathy
10.3760/cma.j.cn321828-20190903-00189
- VernacularTitle:99Tc m-HSA SPECT/CT显像对蛋白丢失性肠病的诊断价值
- Author:
Xiaoguang DU
1
;
Ke SUN
;
Xu WANG
;
Xinli XIE
;
Xin WEN
;
Ruihua WANG
Author Information
1. 郑州大学第一附属医院核医学科、河南省分子影像医学重点实验室 450052
- From:
Chinese Journal of Nuclear Medicine and Molecular Imaging
2020;40(9):523-527
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the diagnostic value of 99Tc m-human serum albumin (HSA) SPECT/CT imaging for protein-losing enteropathy. Methods:Retrospective analysis was performed on 55 patients (21 males, 34 females, age: 5-78 (46.7±13.5) years) who had hypoproteinemia and underwent 99Tc m-HSA SPECT/CT imaging in the First Affiliated Hospital of Zhengzhou University between August 2016 and August 2019. The diagnostic efficiencies of dynamic planar imaging and SPECT/CT imaging for protein-losing enteropathy were evaluated according to the clinical final diagnosis. χ2 test was used for data analysis. Results:The final clinical diagnosis confirmed 46/52 patients were with protein-losing enteropathy. The sensitivities, specificities and accuracies of 99Tc m-HSA planar imaging and SPECT/CT imaging for the diagnosis of protein-losing enteropathy were 91.30% (42/46) vs 100% (46/46), 6/9 vs 8/9, and 87.27% (48/55) vs 98.18%(54/55), respectively. The differences in sensitivity, specificity and accuracy were all statistically significant ( χ2 values: 5.73, 4.27, 5.42, all P<0.05). Conclusion:Based on 99Tc m-HSA planar dynamic imaging, SPECT/CT imaging has good diagnostic ability for intestinal protein loss and high diagnostic efficiency for protein-losing enteropathy.
