Research progress of 6-18F fluoro-L-dopa PET/CT imaging
10.3760/cma.j.issn.2095-2848.2020.02.012
- VernacularTitle:18F-DOPA PET/CT显像的研究进展
- Author:
Jingnan WANG
1
;
Yaping LUO
;
Li HUO
;
Fang LI
Author Information
1. 中国医学科学院、北京协和医学院北京协和医院核医学科、核医学分子靶向诊疗北京市重点实验室 100730
- Keywords:
Levodopa;
Fluorine radioisotopes;
Positron-emission tomography;
Tomography,X-ray computed;
Trends
- From:
Chinese Journal of Nuclear Medicine and Molecular Imaging
2020;40(2):113-117
- CountryChina
- Language:Chinese
-
Abstract:
6-[18F]fluoro-L-dopa (18F-DOPA) is a levodopa analogue.18F-DOPA PET/CT imaging is considered as an ideal tool in the diagnosis and evaluation of Parkinson's disease,brain tumors,pheochromocytoma/paraganglioma,neuroblastoma,gastrointestinal carcinoid,medullary thyroid cancer and congenital hyperinsulinemia.This paper reviews the synthesis,mechanism of localization,imaging procedures,clinical indications and research advances of 18F-DOPA.
