Biomechanical study of injectable calcium sulfate cement
10.3760/cma.j.cn121113-20200330-00195
- VernacularTitle:可注射性硫酸钙骨水泥的生物力学研究
- Author:
Dengxing LUN
1
;
Lina XU
;
Jiangtao FENG
;
Feng WANG
;
Pengsheng WANG
;
Yongcheng HU
Author Information
1. 潍坊市人民医院 261041
- From:
Chinese Journal of Orthopaedics
2020;40(10):661-668
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effect of different plasticizers on the compressive strength of injectable calcium sulfate cement (ICSC).Methods:Hydroxymethylcellulose (CMC), methylcellulose (MC), hyaluronic acid (HA), stearic acid (SA) and self-made hemihydrate calcium sulfate were used to mix them, and the compressive strength of the complex was observed after reaction with normal saline; the changes of ICSC's own properties, such as setting time and injectability, were recorded.Results:The compressive strength of calcium sulfate was 21±4.58 mPa, and the final setting time was 3.86 ± 0.09 min. Different concentrations of SA had no significant effect on the compressive strength of calcium sulfate ( F=1.593, P=0.266), but prolonged the setting time ( F=29.868, P=0.000). CMC with different concentrations significantly reduced the compressive strength of calcium sulfate ( F=23.943, P=0.000), and the setting time was prolonged to more than 120 min. Different concentrations of MC can improve the compressive strength of calcium sulfate ( F=4.808, P=0.034), and prolong the setting time ( F=191.192, P=0.000); among them, 1% and 3% MC can significantly improve the compressive strength ( P=0.007, 0.027). Different concentrations of HA can improve the compressive strength ( F=3.818, P=0.058), and prolong the setting time ( F=262.515, P=0.000), of which 3% and 5% were significantly improved ( P=0.026, 0.015), while 1% group was not significantly improved ( P=0.062). In addition, the injectable properties of HA, MC, stearic acid and CMC are better, respectively. Conclusion:SA and CMC can not be used to improve the compressive strength of calcium sulfate, while HA and MC of appropriate concentration can improve the compressive strength of ICSC, and improve the injectable performance, but MC can make the coagulation time more in line with clinical needs.
