Impact of splenectomy on hemorheology and portal vein thrombosis in patients with cirrhosis and portal hypertension
10.3760/cma.j.cn113884-20191007-00326
- VernacularTitle:肝硬化门静脉高压患者脾切除对血液流变学的影响及血栓形成分析
- Author:
Long HUANG
1
;
Qingsheng YU
;
Binbin GUO
Author Information
1. 安徽中医药大学第一附属医院普外科，合肥 230031
- From:
Chinese Journal of Hepatobiliary Surgery
2020;26(8):581-584
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the changes in hemorheology in cirrhotic patients with portal hypertension before and after splenectomy.Methods:The data on cirrhotic patients with portal hypertension and hypersplenism who underwent splenectomy from January 2018 to May 2019 in the First Affiliated Hospital of Anhui University of Traditional Chinese Medicine was analyzed. The hemorheology indexes were monitored during the perioperative period, and portal vein thrombosis was monitored by Color Doppler ultrasound.Results:A total of 30 patients were included, including 18 males and 12 females; aged 12.0-62.0 (31.7±14.0) years. One week after splenectomy, portal vein thrombosis was found in all the patients and it disappeared after heparin treatment. The leukocyte and bilirubin levels significantly improved after splenectomy ( P<0.05). The viscosity of high, medium and low cut blood, platelet and D-dimer significantly increased ( P<0.05). Conclusions:After splenectomy, blood viscosity and platelets of cirrhotic patients with portal hypertension and hypersplenism increased, and portal vein thrombosis formed easily.
