Complications of nano-knife ablation on locally advanced pancreatic cancer
10.3760/cma.j.cn113884-20190923-00312
- VernacularTitle:局部进展期胰腺癌纳米刀消融术后并发症分析
- Author:
Hao TONG
1
;
Xiaoyong LI
;
Yanjun CHEN
;
Bingbing CHENG
;
Shengyang CHEN
;
Shuiquan HU
;
Dongzhao SU
Author Information
1. 郑州大学第五附属医院肝胆胰腺外科 450052
- From:
Chinese Journal of Hepatobiliary Surgery
2020;26(4):270-273
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the complications of irreversible electroporation (nano-knife) ablation on locally advanced pancreatic cancer, and to analyse the causes of complications and related treatment.Methods:The clinical data of 36 patients with locally advanced pancreatic cancer treated with nano-knife ablation at the Fifth Affiliated Hospital of Zhengzhou University from January 2016 to March 2019 were studied retrospectively. The types and incidence of postoperative complications were analyzed. The complications were classified according to the Clavien-Dindo classification, and the severity of the complications was evaluated.Results:There were 15 patients (41.7%) who developed various degrees of complications, including splenic infarction, atrial fibrillation, portal vein thrombosis, pancreatic fistula, pseudoaneurysm, gastrointestinal bleeding, liver abscess and severe pancreatitis. Among them, 6 patients (16.7%) had grade III complication or above. Three (8.3%) patients with grade Ⅲ complications died of upper gastrointestinal bleeding 3 months after operation.Conclusions:Various complications might occur after nano-knife ablation, with postoperative gastrointestinal and abdominal bleeding being the main complications which resulted in death. Measures which can effectively reduce occurrence of complications need to be studied.
