Prognostic factors in patients with occult ruptured hepatocellular carcinoma after hepatectomy
10.3760/cma.j.issn.1007-8118.2020.03.003
- VernacularTitle:隐匿型破裂的肝细胞癌患者肝切除术后预后影响因素分析
- Author:
Jie KONG
1
;
Zhiyong SUN
;
Wenxin SHI
;
Yongqiang YE
;
Hui LI
;
Haiwang ZHAO
;
Quanbin XU
Author Information
1. 菏泽市立医院肝胆外科，菏泽 274000
- From:
Chinese Journal of Hepatobiliary Surgery
2020;26(3):170-172
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the prognostic factors in patients with occult ruptured hepatocellular carcinoma (HCC) after hepatectomy.Methods:The clinical data of 31 patients with occult ruptured HCC who underwent hepatectomy at the Heze Multiple Hospital from January 2001 to December 2014 were retrospectively analyzed. There were 27 males and 4 females, with ages ranging from 29 to 73 years. Kaplan-Meier survival analysis was carried out for survival analysis, and compared by the log-rank test. Multivariate analysis was conducted using the Cox proportional hazards regression model.Results:Of 31 patients in this study, 27(87.1%) had died, and 25(80.6%) had developed tumor recurrence and metastasis. The median overall survival was 8 months and the median tumor-free survival was 4 months. On Cox regression analysis, non-R 0 resection was an independent risk factor of overall survival ( RR=2.816, 95% CI: 1.006-7.887) and disease-free survival ( RR=3.295, 95% CI: 1.215-8.940). Poor tumor differentiation was an independent risk factor of overall survival ( RR=3.120, 95% CI: 1.193-8.160). Conclusions:The prognosis of patients with occult rupture HCC who underwent no R 0 resection was poor. However, the prognosis of patients who underwent non-R 0 resection was even poorer.
