Progress in research on donor liver preservation technology in vitro
10.3760/cma.j.issn.1007-8118.2020.03.020
- VernacularTitle:供肝体外保存技术的研究进展
- Author:
Huan CAO
1
;
Hongli SONG
;
Zhongyang SHEN
Author Information
1. 天津医科大学一中心临床学院，天津 300192
- From:
Chinese Journal of Hepatobiliary Surgery
2020;26(3):229-233
- CountryChina
- Language:Chinese
-
Abstract:
Liver transplantation is the most effective therapeutic options for the patients at the advanced stage, but with the amount of transplant surgery increasing, margin donors are used for transplantation in the case of severe donor organ deficiency. However, the commonly used cold storage technique has poor preservation effect on margin donors, resulting in an increase in the incidence of complications after transplantation. The donated liver quality is one the most important factors for the patients long term survival, so there is an urgent need for a new type of organ preservation technology to preserve the margin donors in vitro. This paper summarized the current research on the ex-vivo preservation methods of liver and the new mechanical perfusion preservation methods.
