Non-alcoholic fatty liver disease and liver transplantation
10.3760/cma.j.issn.1007-8118.2020.02.017
- VernacularTitle:非酒精性脂肪性肝病与肝移植
- Author:
Pengcheng ZHANG
1
;
Kefeng DOU
;
Zhaoxu YANG
;
Ruohan ZHANG
;
Hongtao ZHANG
;
Wei PENG
;
Yanbing CAO
;
Weimin LI
Author Information
1. 空军医科大学西京医院肝胆外科
- Keywords:
Liver transplantation;
Metabolic syndrome;
Fatty liver,non-alcoholic
- From:
Chinese Journal of Hepatobiliary Surgery
2020;26(2):155-157
- CountryChina
- Language:Chinese
-
Abstract:
Non-alcoholic fatty liver disease (NAFLD) is characterized by increased fat depositions in the liver while the patients do not have drinking history.NAFLD has a prevalence of 10％ ～40％ in global,25％ ～26％ in Western populations.From 2004 to 2013,the numbers of new patients on the waitlist who had NASH increased by 170％ in America.The prevalence of NAFLD in China is 20％.With the decrease of HBV and HCV and the increase of diabetes mellitus type 2 and obesity,NAFLD will become the most common chronic liver disease in China over the next 20 years.NAFLD related end-stage liver disease will become the most common indication of liver transplantation.In this paper,the epidemiological features,pathogenesis,indication and prognosis of liver transplantation are reviewed.
