Timing of radical surgery in patients with postoperative incidentally discovered gallbladder cancer
10.3760/cma.j.issn.1007-8118.2020.02.008
- VernacularTitle:术后意外胆囊癌再次手术时机探讨
- Author:
Xinwei YANG
1
;
Yulong LI
;
Jing DU
;
Zhijian WEN
;
Jue YANG
;
Pinghua YANG
;
Baohua ZHANG
Author Information
1. 海军军医大学东方肝胆外科医院胆道外科
- Keywords:
Gallbladder neoplasms;
Prognosis;
Incidental gallbladder cancer;
Treatment strategy;
Reoperation
- From:
Chinese Journal of Hepatobiliary Surgery
2020;26(2):119-123
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the tumor characteristics and survival between postoperative incidentally discovered gallbladder cancer (ID-GBC) and preoperatively suspected gallbladder cancer (PS-GBC).Methods The data of 276 GBC patients who underwent surgical resection with curative intent between January 2004 and December 2014 at the Eastern Hepatobiliary Surgery Hospital were retrospectively analyzed.Results The 1-,3-,and 5-year cumulative survival rates of the ID-GBC group (88.8％,52.2％,and 33.0％,respectively) were significantly better than those in the PS-GBC group (57.5％,25.7％,and 16.6％,P ＜ 0.05).In the ID-GBC group,multivariate analysis revealed that T staging,hepatic invasion and time interval from cholecystectomy to re-operation were independent prognostic factors.The overall survival (OS) in the group with the time interval within 2 weeks was significantly better than those in the other two groups (both P ＜ 0.05).However,there were no significant differences in OS between the groups with the time interval of 2 weeks to 1 month and more than 1 month (P ＞ 0.05).Conclusions Postoperative ID-GBC had significantly better survival outcomes than PS-GBC.Reoperation within two weeks in patients with ID-GBC is a good strategy.
