Research progress on diagnosis and treatment of HPV-positive oropharyngeal cancer
10.3760/cma.j.cn113030-20190409-00127
- VernacularTitle:HPV阳性口咽癌的诊疗进展
- Author:
Guangmin MAO
1
;
Tingting XU
;
Xueguan LU
Author Information
1. 复旦大学附属肿瘤医院放疗科,上海 200032
- From:
Chinese Journal of Radiation Oncology
2020;29(11):1012-1016
- CountryChina
- Language:Chinese
-
Abstract:
The incidence of human papillomavirus (HPV)-positive oropharyngeal cancer is growing year by year. Compared with the other head and neck squamous cell carcinoma, HPV-positive oropharyngeal cancer has unique biological characteristics and better prognosis. According to the 8 th edition TNM staging of UICC/AJCC, HPV-positive and HPV-negative oropharyngeal cancer have been classified separately. In 2018, College of American Pathologists and American Society of Clinical Oncology released the guidelines on the HPV testing in head and neck cancer. Several published clinical trials have demonstrated that de-intensified chemoradiation might be efficacious treatment of HPV-positive oropharyngeal cancer.