The value of MRI enhanced scan sequence in the radiotherapy target volume delineation in lung cancer with obstructive pneumonia/atelectasis
10.3760/cma.j.cn113030-20180928-00010
- VernacularTitle:磁共振增强扫描序列在合并阻塞性肺炎或肺不张肺癌放疗靶区勾画价值
- Author:
Tianyu HE
1
;
Sihan LI
;
Guang LI
Author Information
1. 中国医科大学附属第一医院放疗科，沈阳 110000
- From:
Chinese Journal of Radiation Oncology
2020;29(5):369-373
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the feasibility and advantages of different MRI sequences in delineating target volumes in lung cancer with obstructive pneumonia or atelectasis (OC).Methods:Fourteen patients with OC underwent CT localization and MRI scan. CT, T 1WI, fat suppression T 2WI, LAVA, LAVA+ C images were collected respectively. CT and MRI images were fused in the treatment planning system, and GTV-p was target delineated on CT and MRI respectively. Results:CT showed tumor and OC boundaries in 2 patients, fat suppression T 2WI showed tumor and OC boundaries in 10 patients, LAVA showed tumor and OC boundaries in 12 patients, and LAVA+ C showed tumor and OC boundaries in 10 patients. Fat suppression T 2WI, LAVA, and LAVA+ C sequences showed similar resolving ability ( P>0.05). The GTV of T 2WI, LAVA, and LAVA+ C sequences decreased significantly compared with ST-GTV ( P<0.05), and T 2WI_GTV and LAVA_GTV were similar ( P>0.05). The GTV value of LAVA+ C was the smallest among all sequences. Conclusions:The application of MRI fat compression T 2WI, LAVA, and LAVA+ C sequences to the radiotherapy target volume delineation in lung cancer patients with OC improved the accuracy, among which the boundary resolution of LAVA was better than that of fat compression T 2WI, and LAVA+ C showed the best effect on tiny blood vessels.
