Research progress on biomarkers for radiation-induced intestinal injury based on intestinal flora
10.3760/cma.j.issn.1004-4221.2020.03.018
- VernacularTitle:基于肠道菌群的肠放射损伤生物标记物研究进展
- Author:
Junjun ZHANG
1
;
Shang CAI
;
Yongqiang YANG
;
Junyan LI
;
Ye TIAN
Author Information
1. 苏州大学附属第二医院放疗科苏州大学放射肿瘤治疗学研究所苏州市肿瘤放射治疗学重点实验室 215004
- Keywords:
Intestinal flora;
Metabolite;
Radiation-induced injury;
Biomarker
- From:
Chinese Journal of Radiation Oncology
2020;29(3):237-240
- CountryChina
- Language:Chinese
-
Abstract:
Recently,the relationship between intestinal flora and its metabolites and tumorigenesis,inflammatory bowel diseasesas well as radiation-induced intestinal injury has captivated widespread attention from researchers.Accumulated evidence derived from nuclear accident investigation,animal model experiment and clinical research has proven the role of intestinal flora and its metabolites as the biomarkers to evaluate the radiation dose and severity of radiation-induced intestinal injury.This article reviews the relationship between intestinal flora and its metabolites and radiation-induced intestinal injury,aiming to provide theoretical reference for assessing the risk of radiation-induced intestinal injury.
