Evaluation of cost-effective ratio (imaging quality vs. radiation dose) of Varian cone beam CT based on figure of merit (FOM)
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3760/cma.j.issn.0254-5098.2020.08.004
   		
        
        	
        		- VernacularTitle:基于品质因素评价瓦里安锥束CT成像质量与辐射剂量风险收益比
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Junyu LI
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Hao WU
			        		
			        		;
		        		
		        		
		        		
			        		Jingxian YANG
			        		
			        		;
		        		
		        		
		        		
			        		Tingting LI
			        		
			        		;
		        		
		        		
		        		
			        		Songmao YU
			        		
			        		;
		        		
		        		
		        		
			        		Zihong LU
			        		
			        		;
		        		
		        		
		        		
			        		Meijiao WANG
			        		
			        		;
		        		
		        		
		        		
			        		Chenguang LI
			        		
			        		;
		        		
		        		
		        		
			        		Weibo LI
			        		
			        		;
		        		
		        		
		        		
			        		Yibao ZHANG
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. 北京大学肿瘤医院暨北京市肿瘤防治研究所放疗科 恶性肿瘤发病机制及转化研究教育部重点实验室 100142
			        		
		        		
	        		
        		 
        	
        	
        	
        	
            
            
            	- From:
	            		
	            			Chinese Journal of Radiological Medicine and Protection
	            		
	            		 2020;40(8):595-599
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
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		        	Abstract:
			       	
			       		
				        
				        	Objective:To analyze and compare the radiation dose and image quality of kilo-voltage cone beam CT systems on different Varian accelerator platforms, providing data to support clinical decisions on selecting optimal protocols for image-guided radiotherapy based on cost-effective ratio (image quality / radiation dose).Methods:The radiation dose and image quality of various CBCT systems and scanning protocols on Varian Edge, Truebeam and ix (new and old) LINACs were obtained using a CT dose index (CTDI) phantom combined with a CT ionization chamber and a Catphan604 phantom, respectively. Figure of merit (FOM) was used to evaluate the cost-effective ratio of the image guidance schemes.Results:Considerable inter-system varieties of FOMs were observed, varying from 0.65 (Image Gently-full trajectory) to 48.46 (Image Gently-half trajectory). The inter-protocol varieties were also large, where the mean±SD was 22.14±13.47.Conclusions:Considering the explicit inter-system and inter-protocol varieties, it is clinically favorable to evaluate the image guidance schemes based on machine-specific measurement. For instance, parameters and equipment with low CTDI w can be beneficial for dose-sensitive patients. High CNR regimen favors patients with high image quality requirements. For ordinary patients, cost-effective ratio in terms of FOM can be very helpful to guide the decision-making of clinical image-guided radiotherapy.