The value of tumor blood supply characteristics of arterial phase in evaluating the prognosis of patients with intrahepatic mass-forming cholangiocarcinoma
10.3760/cma.j.cn112149-20190618-00497
- VernacularTitle:动脉期肿瘤血供特征在评估肿块型肝内胆管细胞癌患者预后中的价值
- Author:
Bingrong LI
1
;
Kun ZHANG
;
Liuxiao ZHOU
;
Liyan LEI
;
Xuemiao ZHAO
;
Xihui YING
;
Chenying LU
;
Yangrui XIAO
;
Xiao CHEN
;
Jiansong JI
;
Zhongwei ZHAO
;
Xinmu ZHOU
Author Information
1. 浙江省影像诊断及介入微创重点实验室 丽水市中心医院放射科 323000
- From:
Chinese Journal of Radiology
2020;54(6):563-567
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the correlation between the enhancement characteristics in arterial phase and the prognosis of patients with massive intrahepatic cholangiocarcinoma (IMCC).Methods:The imaging and clinical data of 92 patients with IMCC who were pathologically confirmed and underwent enhanced MRI or CT in Central Hospital of Lishui from June 2004 to February 2019 were retrospectively analyzed. According to the enhancement pattern of the primary lesion in the arterial phase, patients were divided into rich arterial blood supply group （17 cases） and deficient arterial blood supply group （75 cases）. The clinical data and imaging features of these patients were studied. Differences between measurement data and count data between the two groups were compared using t test and Fisher test. Kaplan-Meier analysis and log-rank test were used to analyze overall survival. The Cox regression multivariate analysis was used to study the relationship between the variables and the risk of death. Result:The enlargement of lymph nodes, long diameter of the primary lesion, CA19-9, treatment and HPD around the primary lesion in arterial phase were statistically different in the two groups ( P<0.05), others were no statistical difference. CA19-9>200 U/ml, lymph node enlargement, HPD around the primary lesion in arterial phase and deficient arterial blood supply were independent factors for the prediction of prognosis in IMCC patients with surgery ( P values were 0.008, 0.002, 0.049 and 0.005, respectively). Lymph node enlargement and deficient arterial blood supply were independent risk factors for the prediction of prognosis in IMCC patients with surgery ( P values are 0.049 and 0.045, respectively). Conclusion:The blood supply characteristics of arterial phase are independent factors for the prognosis of patients with IMCC.
