Coexistence of ankylosing spondylitis and Beh?et's disease associated with antiphospholipid syndrome: a case report and literature review
10.3760/cma.j.c141217-20200506-00186
- VernacularTitle:强直性脊柱炎合并白塞病继发抗磷脂综合征一例并文献复习
- Author:
Yajuan YAO
1
;
Xiaoying WANG
;
Yunjing BAI
;
Fan WU
;
Xiaohua XU
;
Dexun JIANG
Author Information
1. 解放军总医院第七医学中心风湿免疫科，北京 100700
- From:
Chinese Journal of Rheumatology
2020;24(9):622-625
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the clinical features and diagnosis of coexistence of ankylosing spondylitis (AS) and Beh?et's disease associated with antiphospholipid syndrome (APS).Methods:We analyzed a case of coexistence of ankylosing spondylitis and Beh?et's disease associated with APS in Seventh Medical Center of Chinese PLA General Hospital in 2016, and the related literature were reviewed.Results:A 26-year-old male patient suffered from inflammatory low back pain, arthralgia and iritis. A His CT imaging revealed bilateral grade Ⅱ of bilateral sacroiliac arthritis. He was diagnosed as AS. He also had recurrent oral ulceration, iritis, vascular disorders and positive acupuncture pathergy test. He was diagnosed as Beh?et's disease. He suffered from recurrentpeated venous thrombosis. Laboratory tests revealed positive antiphospholipid antibodies. He was diagnosed as secondary APS complicated with Beh?et's disease. After he was treated with of glucocorticosteroid, cyclophosphamide, adalimumab and dabigatran, his condition improved significantly.Conclusion:There are some cases reported of AS with Beh?et's disease, or Beh?et's disease with APS, or AS with APS. The relationship between them is complex. The possibility of coexistence of AS and Beh?et's disease and APS should not be ignored, in order to avoid misdiagnosis.
