Correlation between hyperuricemia and cardiovascular metabolic index in non-obese people
10.3760/cma.j.c141217-20190619-00228
- VernacularTitle:高尿酸血症与心血管代谢指数在非肥胖人群中的相关性研究
- Author:
Jianqin ZHU
1
;
Xingzhen LIU
;
Xia XU
;
Ying GAO
;
Dongbao ZHAO
Author Information
1. 江苏省靖江市人民医院风湿免疫科 214500
- From:
Chinese Journal of Rheumatology
2020;24(7):462-465
- CountryChina
- Language:Chinese
-
Abstract:
Objective:This study explored the correlation between Cardiovascular metabolic index (CMI) and hyperuricemia (HUA) in non-obese Chinese population.Methods:73 150 non-obese people who received routine physical examination between January 2014 to December 2017 were included in this cross-sectional study (from Jingjiang People's Hospital of Jiangsu Province, Hangzhou Aeronautical Sanatorium of Chinese Air Force, and Shanghai Changhai Hospital). The anthropometric indexes, lipid parameters including triglycerides, and high-density lipoprotein cholesterol, uric acid, and other clinical parameters were collected, and the CMI values were calculated from the waist-to-body ratio (WHtR). The correlation between CMI and HUA was analyzed by Logistic regression model.Results:Among 39 443 non-obese women, 5 825 patients were HUAs with a prevalence rate of 14.7%; among 33 707 non-obese men, 7 720 were HUAs with a prevalence rate of 22.9%. HUA had no significant association with Waist-to-Hip Ratio (WHR) and WHtR, but only with CMI. The highest quartile of women in CMI was 6.311(5.734, 6.947) and 6.785(6.092, 7.557) in male, P<0.01. Conclusion:CMI is significantly associated with HUA in non-obese Chinese population and is expected to become a new monitoring parameter for the prevention and management of HUA and gout.
