Ankylosing spondylitis coexistent with systemic lupus erythematosus: 8 cases reports and review of the literature
10.3760/cma.j.cn141217-20190530-00208
- VernacularTitle:强直性脊柱炎合并系统性红斑狼疮八例并文献复习
- Author:
Qihong GUO
1
;
Xiaojuan ZHANG
;
Ting LI
;
Meixing YE
;
Jia ZENG
;
Baolin ZHENG
Author Information
1. 广州中医药大学附属佛山中医院风湿科 528000
- From:
Chinese Journal of Rheumatology
2020;24(4):264-267
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To summary the clinical features of 8 cases with ankylosing spondylitis (AS) complicated with systemic lupus erythematosus (SLE).Methods:This study was conducted retrospectively from January 2007 to November 2018. Eight patients with AS complicated with SLE who were admitted to Foshan Hospital of TCM were analyzed. Bath ankylosing spondylitis disease activity index (BASDAI) was compared using t-test. Results:Four patients were female. The mean age was (31±14) years, ranged from 16 to 59 years. The average disease duration of AS was (27±30) months(ranging from 4 to 144 months). The average disease of duration SLE was (69±51) months (ranging from 1 to 80 months). All patients was human lymphocyte antigen (HLA)-B27 positive. SLE-related organ involvement included kidney in 5 cases, leukocytopenia in 8 cases, arthralgia in 6 cases, nervous system in 1 case and skin rash in 3 cases. Renal biopsy were performed in 3 patients. And 2 cases were class Ⅲ+Ⅴ lupus nephritis, another one was class Ⅳ+Ⅴ lupus nephritis.Conclusion:AS may complicated with SLE. Some drugs may be able to active the potential SLE, which should be differentiated from drug-related lupus.
